Portrait of Daniel Parker, MD

Daniel Parker, MD

Daniel Parker, MD is a board-certified internist and geriatrician, memory disorders specialist, and translational researcher whose work focuses on the intersection of biological aging and cognitive health.

Associate Professor of Medicine

Associate Professor of Neurology

Medical Director, Duke Memory Disorders Clinic

Duke University School of Medicine

Curriculum Vitae

Current Positions

Associate Professor — Duke University School of Medicine, Department of Medicine, Division of Geriatrics — Durham, NC — January 2025 – Current

Associate Professor — Duke University School of Medicine, Department of Neurology — Durham, NC — 2026 – Current

Senior Fellow — Duke University Center for the Study of Aging and Human Development — Durham, NC — 2019 – Current

Medical Director, Memory Disorders Clinic — Duke Neurological Disorders Clinic at Morreene Road — Durham, NC — December 2024 – Current

Attending Physician — Duke Regional Hospital — Durham, NC — July 2019 – Current

Academic Appointment History at Duke

  • Geriatric Medicine Fellow, Duke University Medical Center — July 2016 – June 2017
  • Advanced Fellow, Geriatric Medicine, Duke University Medical Center — July 2017 – June 2019
  • Post-Doctoral Scholar (T32), Duke Aging Center — July 2017 – June 2019
  • Medical Instructor, Duke University Medical Center — July 2019 – November 2020
  • Assistant Professor, Duke University Medical Center — November 2020 – December 2024
  • Associate Professor, Duke University Medical Center — January 2025 – Current

Education

Master of Health Science (MHS) in Clinical Research — Duke University School of Medicine, Clinical Research Training Program — Durham, NC — conferred 2023

Post-Doctoral Research Fellow — Duke University Center for the Study of Aging and Human Development — Durham, NC — 2017 – 2019

Advanced Fellow in Geriatric Medicine — Duke University School of Medicine — Durham, NC — 2017 – 2019

Fellow in Geriatric Medicine — Duke University School of Medicine — Durham, NC — 2016 – 2017

Residency in Internal Medicine — Eastern Virginia Medical School — Norfolk, VA — 2013 – 2016

Doctor of Medicine (MD) — Eastern Virginia Medical School — Norfolk, VA — 2009 – 2013

B.S., Psychology and B.A., German Studies — University of North Carolina at Chapel Hill — 2000 – 2005

Board Certification and Licensure

Geriatric Medicine — American Board of Internal Medicine — November 2017

Internal Medicine — American Board of Internal Medicine — August 2016

North Carolina Medical License — issued June 2016, active

Honors and Awards

  • Best Paper Award, "ClinSTAR" Paper Session — American Geriatrics Society Annual Scientific Meeting — May 2022
  • Health in Aging Foundation New Investigator Award — American Geriatrics Society — May 2020
  • Poster Presentation Award of Recognition — Duke Protein Biomarkers in Precision Medicine Colloquium — November 2019
  • Poster Presentation Award of Recognition — Claude D. Pepper Older American Independence Centers Annual Meeting — April 2019
  • Trainee Travel Scholarship Award — NINDS Alzheimer's-Disease Related Dementias Summit, Bethesda, MD — March 2019
  • Trainee Travel Scholarship Award — NIA-AGS Osteoporosis and Soft Tissue Disorders Workshop, Bethesda, MD — March 2019
  • Robert J. Lefkowitz Society — Duke University School of Medicine — July 2018
  • Summer Training Course on the Biology of Aging Scholar — Buck Institute for Research on Aging — 2018
  • George Maddox Fellow / George Maddox Award — Duke Center for the Study of Aging and Human Development — August 2017
  • James P. Baker, MD Award (outstanding graduating internal medicine resident) — Eastern Virginia Medical School — June 2016
  • Department of Medicine 35th Annual Research Day, 1st Place Award — Eastern Virginia Medical School — June 2016
  • Alpha Omega Alpha Honor Medical Society — May 2015
  • Department of Medicine Intern of the Year Award — Eastern Virginia Medical School — June 2014
  • Gold Humanism Honor Society — May 2012
  • Start Norfolk 2012 Pitch Competition, 3rd Place — OurCareDirect.com — May 2012
  • Innovations in Aging Best Practices Award, 2nd Place — Virginia Commonwealth Council on Aging — May 2012
  • Heroes Award for Exemplary Community Service — Eastern Virginia Medical School — April 2011
  • Medical Students Training in Aging Research Summer Scholar — NIA / Johns Hopkins School of Medicine — May 2010

Peer-Reviewed Publications

  1. Levesque MC, Moody MA, Hwang KK, Marshall DJ, Whitesides JF, Amos JD, Gurley TC, Allgood S, Haynes BB, Vandergrift NA, Plonk S, Parker DC, Cohen MS, Tomaras GD, Goepfert PA, Shaw GM, Schmitz JE, Eron JJ, Shaheen NJ, Hicks CB, Liao H, Markowitz M, Kelsoe G, Margolis DM, Haynes BF. Polyclonal B cell differentiation and loss of gastrointestinal tract germinal centers in the earliest stages of HIV-1 infection. PLoS Medicine. 2009. doi:10.1371/journal.pmed.1000107

  2. Archin NM, Espeseth A, Parker DC, Cheema M, Hazuda D, Margolis DM. Expression of latent HIV induced by the potent HDAC inhibitor suberoylanilide hydroxamic acid. AIDS Research and Human Retroviruses. 2009;25(2):207–212. doi:10.1089/aid.2008.0191

  3. Archin NM, Cheema M, Parker DC, Wiegand A, Bosch RJ, Coffin JM, Eron J, Cohen M, Margolis DM. Antiretroviral intensification and valproic acid lack sustained effect on residual HIV-1 viremia or resting CD4+ cell infection. PLoS ONE. 2010;5(2):e9390. doi:10.1371/journal.pone.0009390

  4. Anderson JA, Archin NM, Ince W, Parker DC, Wiegand A, Coffin JM, Kuruc J, Eron J, Swanstrom R, Margolis DM. Clonal sequences recovered from plasma from patients with residual HIV-1 viremia and on intensified antiretroviral therapy are identical to replicating viral RNAs recovered from circulating resting CD4+ T cells. Journal of Virology. 2011;85(10):5220–5223. doi:10.1128/JVI.00284-11

  5. Archin NM, Liberty AL, Kashuba AD, Choudhary SK, Kuruc JD, Crooks AM, Parker DC, Anderson EM, Kearney MF, Strain MC, Richman DD, Hudgens MG, Bosch RJ, Coffin JM, Eron JJ, Hazuda DJ, Margolis DM. Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy. Nature. 2012;487(7408):482–485. doi:10.1038/nature11286

  6. Parker DC, Mielke MM, Yu Q, Rosenberg PB, Jain A, Lyketsos CG, Fedarko NS, Oh ES. Plasma neopterin level as a marker of peripheral immune activation in amnestic mild cognitive impairment and Alzheimer's disease. International Journal of Geriatric Psychiatry. 2013;28(2):149–154. doi:10.1002/gps.3802

  7. Morey MC, Lee CC, Castle S, Valencia WM, Katzel L, Giffuni J, Kopp T, Cammarata H, McDonald M, Oursler KA, Wamsley T, Jain C, Bettger JP, Pearson M, Manning KM, Intrator O, Veazie P, Sloane R, Li J, Parker DC. Should structured exercise be promoted as a model of care? Dissemination of the VA Gerofit Program. Journal of the American Geriatrics Society. 2018;66(5):1009–1016. doi:10.1111/jgs.15276

  8. Parker DC, Sloane R, Pieper CF, Hall KS, Kraus VB, Kraus WE, Huebner JL, Ilkayeva OR, Bain JR, Newby LK, Cohen HJ, Morey MC. Age-related adverse inflammatory and metabolic changes begin early in adulthood. The Journals of Gerontology: Series A. 2019;74(3):283–289. doi:10.1093/gerona/gly121

  9. Colón-Emeric C, Whitson HE, Pieper CF, Sloane R, Orwig D, Huffman KM, Prvu Bettger J, Parker DC, Crabtree DM, Gruber-Baldini A, Magaziner J. Resiliency groups following hip fracture in older adults. The Journals of Gerontology: Series A. 2019;67(12):2519–2527. doi:10.1111/jgs.16152

  10. Parker DC, Bryce B, Cohen HJ, Fillenbaum G, Huebner J, Kraus VB, Pieper CF, Belsky DW. Association of blood chemistry quantifications of biological aging with disability and mortality in older adults. The Journals of Gerontology: Series A. 2019. doi:10.1093/gerona/glz219

  11. Zhou J, Parker DC (co-first author), White JP, Lim A, Huffman KM, Yen P, Kraus WE. Thyroid hormone status regulates skeletal muscle response to chronic motor nerve stimulation. Frontiers in Physiology — Integrative Physiology. 2019;10:1363. doi:10.3389/fphys.2019.01363

  12. Parker DC, Colón-Emeric C, Huebner JL, Chou CH, Kraus VB, Pieper CF, Sloane R, Whitson HE, Orwig D, Crabtree DM, Magaziner J, Bain JR, Ilkayeva OR, Huffman KM. Biomarkers associated with physical resilience after hip fracture. The Journals of Gerontology: Series A. 2020. doi:10.1093/gerona/glaa119

  13. Ramalingam S, Siamakpour-Reihani S, Bohannan L, Ren Y, Sibley A, Sheng J, Ma L, Nixon AB, Lyu J, Parker DC, Bain J, Muehlbauer M, Ilkayeva O, Kraus VB, Huebner JL, Spitzer T, Brown J, Peled JU, van den Brink M, Gomes A, Choi T, Gasparetto C, Horwitz M, Long G, Lopez R, Rizzieri D, Sarantopoulos S, Chao N, Sung AD. A phase 2 trial of the somatostatin analog pasireotide to prevent GI toxicity and acute GVHD in allogeneic hematopoietic stem cell transplant. PLoS ONE. 2021. doi:10.1371/journal.pone.0252995

  14. Whitson HE, Crabtree D, Pieper CF, Ha C, Au S, Berger M, Cohen HJ, Feld J, Smith P, Hall K, Parker DC, Kraus VB, Kraus WE, Schmader K, Colón-Emeric C. A template for physical resilience research in older adults: Methods of the PRIME-KNEE study. Journal of the American Geriatrics Society. 2021. doi:10.1111/jgs.17384

  15. Huffman KM, Parker DC, Bhapkar M, Racette SB, Martin CK, Redman LM, Das SK, Connelly MA, Pieper CF, Orenduff M, Ross LM, Ramaker ME, Dorling JL, Rosen CJ, Shalaurova I, Otvos JD, Kraus VB, Kraus WE. Calorie restriction improves lipid-related emerging cardiometabolic risk factors in healthy adults without obesity: Distinct influences of BMI and sex from CALERIE, a multicentre, phase 2, randomised controlled trial. eClinicalMedicine. 2022. doi:10.1016/j.eclinm.2021.101261

  16. Parker DC, Wan M, Lohman K, Hou L, Nguyen AT, Ding J, Bertoni A, Shea S, Burke GL, Jacobs DR, Post W, Corcoran DL, Hoeschele I, Parks JS, Liu Y. Monocyte miRNAs are associated with type 2 diabetes. Diabetes. 2022;71(4):853–861. doi:10.2337/db21-0704

  17. Eckhoff AM, Connor AA, Thacker JKM, Blazer DG, Moore HG, Scheri RP, Lagoo-Deenadayan SA, Harpole DH, Seymour KA, Purves JT, Ravindra KV, Southerland KW, Rocke DJ, Gilner JB, Parker DC, Bain JR, Muehlbauer MJ, Ilkayeva OR, Corcoran DL, Modliszewski JL, Devos N, Foster MW, Moseley MA, Dressman HK, Chan C, Huebner JL, Chasse S, Stempora L, Aschenbrenner ME, Joshi M, Hollister B, Henao R, Barfield RT, Elison MA, Bailey S, Woody S, Huang ES, Kirk A, Hwang ES. A multidimensional bioinformatic platform for the study of human response to surgery. Annals of Surgery. 2022;275(6):1094–1102. doi:10.1097/SLA.0000000000005429

  18. Erickson ML, Wang W, Counts J, Redman LM, Parker D, Huebner JL, Dunn J, Kraus WE. Field-based assessments of behavioral patterns during shiftwork in police academy trainees using wearable technology. Journal of Biological Rhythms. 2022;37(3):260–271. doi:10.1177/07487304221087068

  19. Kraus VB, Ma S, Tourani R, Fillenbaum GG, Burchett BM, Parker DC, Kraus WE, Connelly MA, Otvos JD, Cohen HJ, Orenduff MC, Pieper CF, Zhang X, Aliferis CF. Causal analysis identifies small HDL particles and physical activity as key determinants of longevity of older adults. EBioMedicine. 2022. doi:10.1016/j.ebiom.2022.104292

  20. Waziry R, Ryan CP, Corcoran DL, Huffman KM, Kobor MS, Kothari M, Graf GH, Kraus VB, Kraus WE, Lin DTS, Pieper CF, Ramaker ME, Bhapkar M, Das SK, Ferrucci L, Hastings WJ, Kebbe M, Parker DC, Racette SB, Shalev I, Schilling B, Belsky DW. Effect of long-term caloric restriction on DNA methylation measures of biological aging in healthy adults from the CALERIE trial. Nature Aging. 2023. doi:10.1038/s43587-022-00357-y

  21. Parker DC, Kraus WE, Whitson HE, Kraus VB, Smith PJ, Cohen HJ, Pieper CF, Faldowski RA, Hall KS, Huebner JL, Ilkayeva OR, Bain JR, Newby LK, Huffman KM. Tryptophan metabolism and neurodegeneration: Longitudinal associations of kynurenine pathway metabolites with cognitive performance and plasma Alzheimer's disease and related dementias biomarkers in the Duke Physical Performance Across the LifeSpan study. Journal of Alzheimer's Disease. 2023. doi:10.3233/JAD-220906

  22. Arbeev KG, Ukraintseva S, Bagley O, Duan H, Wu D, Akushevich I, Stallard E, Kulminski A, Christensen K, Feitosa MF, O'Connell JR, Parker D, Whitson H, Yashin AI. Interactions between genes involved in physiological dysregulation and axon guidance: role in Alzheimer's disease. Frontiers in Genetics. 2023. doi:10.3389/fgene.2023.1236509

  23. Parker DC, Whitson HE, Smith PJ, Kraus VB, Huebner JL, North R, Kraus WE, Cohen HJ, Huffman KM. Anti-CMV IgG seropositivity is associated with plasma biomarker evidence of Aβ accumulation. Journal of Alzheimer's Disease. 2024. doi:10.3233/JAD-230220

  24. Ding J, Nguyen AT, Lohman K, Hensley MT, Parker D, Hou L, Taylor J, Voora D, Sawyer JK, Boudyguina E, Bancks MP, Bertoni A, Pandow JS, Rotter JL, Goodarzi MO, Tracy RP, Murdoch DM, Rich SS, Psaty BM, Siscovick D, Newgard C, Herrington D, Hoeschele I, Shea S, Stein JH, Patel M, Post W, Jacobs D, Parks JS, Liu Y. LXR signaling pathways link cholesterol metabolism with risk for prediabetes and diabetes. Journal of Clinical Investigation. 2024. doi:10.1172/JCI173278

  25. Patel H, Wisely CE, Robbins CB, Parker D, Challa P, Grewal DS, Fekrat S. Aqueous and plasma levels of phosphorylated tau 181 in individuals with normal cognition. Journal of Alzheimer's Disease. 2024. doi:10.3233/JAD-240279

  26. Zhao W, Robbins CB, Grewal DS, Patel H, Soundararajan S, Liu AJ, Johnson KG, Agrawal R, Petrella JR, Stinnett SS, Parker D, Fekrat S. Correlating retinal and choroidal vascular parameters with volumetric MRI in Alzheimer's disease and amnestic mild cognitive impairment. BMC Ophthalmology. 2025;25(1):365. doi:10.1186/s12886-025-04157-x

  27. Liu AJ, Moghadam AA, Alam MS, Lutz MW, Navarra A, Luo S, Wang LA, Petrella JR, Whitson H, O'Brien RJ, Johnson KG, Parker D, Beam C, Sanfilippo M, Al-Sahlani H, Cobb S, Liu MY, Doraiswamy PM. Clinical practice outcomes with lecanemab for Alzheimer disease. Neurology Open Access. 2026;2(3):e000121. doi:10.1212/WN9.0000000000000121

Abstracts and Posters

  1. Chacko TP, Broderick G, Moore N, Parker DC, Kraus WE, Huffman KM. A knowledge-driven bio-behavioral network model of the inflammasome and caloric restriction. Gerontological Society of America Annual Scientific Meeting, Tampa, FL. 2023.
  2. Johnson KJ, Perry C, Parker DC, Liu AL, Beam C, Sanfilippo M, Lutz M, O'Brien R. Creation of a memory disorders clinic biorepository to characterize a clinic population and accurately refer to research studies. Alzheimer's Association International Conference, Boston, MA. 2023.
  3. Parker DC, Kraus WE, Huffman KM, Morey MC, Hall KS, Cohen HJ. Association of plasma inflammatory and metabolic biomarkers with plasma ADRD biomarkers in community-dwelling older adults. Alzheimer's Association International Conference, Virtual. 2022.
  4. Parker DC, Morey MC, Hall KS, Kraus VB, Huebner JL, Cohen HJ. Associations of YKL-40, GDF-15, eotaxin, and MCP-1 with physical and cognitive performance in the Duke PALS Study. Claude D. Pepper OAIC Annual Meeting, Washington, DC. 2022.
  5. Mitchell C, Morey M, Sloane R, Parker DC, Cohen H, Hall K. Two-year changes in physical activity domains across the lifespan: Impact of age and gender. American Geriatrics Society Annual Scientific Meeting. 2021.
  6. Ross LM, Tourani R, Ma S, Shen S, Parker DC, Huffman KM, Kraus VB, Aliferis CF, Kraus WE. Utilizing causal pathway analysis to predict change in cardiorespiratory fitness in the STRRIDE randomized trials. American College of Sports Medicine Annual Meeting, San Francisco, CA. 2020.
  7. Parker DC, Kraus VB, Huebner JL, Pieper CF, Cohen HJ, Belsky DW. Quantifications of biological aging predict disability and mortality in older adults in the Duke EPESE. Gerontological Society of America Annual Scientific Meeting, Austin, TX. 2019.
  8. Parker DC, Huffman KM, Morey M, Hall KS, Kraus WE, Pieper CF, Sloane R, Cohen HJ. Data-driven cluster analysis identifies unique inflammatory and metabolic signatures associated with self-rated health, cognitive and physical performance. Claude D. Pepper OAIC Annual Meeting, Washington, DC. 2019.
  9. Parker DC, Counts JD, Upchurch G, Maxson P, Krol M, Black M, Heflin MT. Connecting Agencies, Practices and Seniors through a Trusted Online Network (CAPSTONe). American Geriatrics Society Annual Scientific Meeting, Portland, OR. 2019.
  10. Parker DC, Kraus VB, Huebner JL, Pieper CF, Cohen HJ, Belsky DW. Quantifications of biological aging predict disability and mortality in older adults in the Duke EPESE. AGS Annual Scientific Meeting Presidential Poster Session, Portland, OR. 2019.
  11. Jin Z, Parker DC, White J, Kraus WE, Huffman KM, Yen PM. Thyroid hormone state interacts with chronic motor nerve stimulation in skeletal muscle fiber-type transitions in a rabbit exercise model. ACSM Integrative Physiology of Exercise Meeting, San Diego, CA. 2018.
  12. Counts JD, Hook BE, Slentz CA, Ross LM, Layton ML, Fos LB, Parker DC, Huffman KM, Kraus WE. Variability in daily step counts with shift work-related circadian rhythm disruption. ACSM Integrative Physiology of Exercise Meeting, San Diego, CA. 2018.
  13. Parker DC, Sloane R, Pieper C, Cohen HJ, Kraus V, Kraus W, Morey M. Age-related deleterious inflammatory and metabolic changes begin early in the lifespan. American Geriatrics Society Annual Scientific Meeting, Orlando, FL. 2018.
  14. Parker DC, Hecht-Leavett C, Cunningham T, Jaskowiak M, Okhravi H. Comparison of visual ratings by community-based radiologists vs. automated ratings of hippocampal atrophy. AGS Annual Scientific Meeting Presidential Poster Session, San Antonio, TX. 2017.
  15. Parker DC, Hall K, Sloane R, Pieper C, Cohen H, Morey M. Sedentary behavior is not independently associated with adverse inflammatory and metabolic changes. AGS Annual Scientific Meeting Presidential Poster Session, San Antonio, TX. 2017.
  16. Parker DC, Jain A, Fedarko NS. The activity of carnosinase, an enzyme enriched in the brain, increases with age. American Geriatrics Society Annual Scientific Meeting, National Harbor, MD. 2011.
  17. Parker DC, Mielke MM, Yu Q, Rosenberg PB, Jain A, Fedarko NS, Lyketsos CG, et al. Elevated plasma neopterin in Alzheimer's disease compared to amnestic mild cognitive impairment. American Geriatrics Society Annual Scientific Meeting, National Harbor, MD. 2011.
  18. Schriber M, Siddiqi S, Parker D, Dunstan M, Galicia-Castillo M, Aravich P. EVMS "Beyond Clinic Walls" student home visit project. American Geriatrics Society Annual Scientific Meeting, National Harbor, MD. 2011.
  19. Valentino C, Parker D. Forming local partnerships to establish a student-run free clinic. Society of Student Run Free Clinics International Conference, Houston, TX. 2011.

Invited Presentations

  1. Reimagining Alzheimer’s Care: The Advent of Subcutaneous Administration of Anti-Amyloid Therapy. South Carolina Neurological Association Annual Meeting. September 12, 2026. Asheville, NC.
  2. Updates on Alzheimer’s Disease Therapeutics. American Geriatrics Society Annual Scientific Meeting Preconference. April 29, 2026. Virtual.
  3. Amyloid Removal Therapy for Early Alzheimer's Disease. Division of General Internal Medicine Grand Rounds, Duke University School of Medicine. February 25, 2026.
  4. Dementia 101. Duke Dementia Family Support Program. February 9, 2026. Virtual.
  5. Diagnosis of Dementia. VAMC Home Based Primary Care Presentation. October 23, 2025.
  6. Emerging Treatments for Dementia. Duke Osher Lifelong Learning Institute. October 14, 2025.
  7. Dementia 101. Duke Dementia Family Support Program Memory Makers Program. October 9, 2025.
  8. Emerging Diagnostic Approaches for Alzheimer's Disease. Duke Dementia Family Support Program Memory Makers Program. September 29, 2025. Virtual.
  9. Early Intervention, Lifelong Support: Anti-Amyloid Therapies and Longitudinal Dementia Care. Department of Medicine Grand Rounds, Duke University School of Medicine. March 28, 2025.
  10. Anti-Amyloid Therapy for Early Alzheimer's Disease: What SNFists and LTC Providers Need to Know. Post-Acute and Long-Term Care Society Annual Meeting. March 11, 2025.
  11. Advances in Diagnosis and Treatment of Early Alzheimer's Disease. Oklahoma University Health Sciences Center Annual Innovations in Aging Conference. March 11, 2025. Virtual.
  12. Anti-Amyloid Therapy for Early Alzheimer's Disease. North Carolina Neurological Society Annual Meeting. March 1, 2025.
  13. Anti-Amyloid Therapy for Early Alzheimer's Disease. Division of Geriatric Medicine Grand Rounds, Duke University School of Medicine. February 28, 2025.
  14. Advances in Alzheimer's Disease: Prevention, Diagnosis, and Treatment. VA COACH Program Retreat. September 15, 2024. Virtual.
  15. Updates in the Diagnosis and Management of Dementia and Alzheimer's. Outer Banks Dementia Friendly Coalition Caregiver Education Conference. April 22, 2024. Kill Devil Hills, NC.
  16. Lecanemab. Duke Dementia Family Support Program. April 15, 2024. Virtual.
  17. Medications & Dementia. Duke Dementia Family Support Program. January 29, 2024. Virtual.
  18. Clinical Biomarker and DNAm-derived Biological Age Measures in a Surgical Cohort. Gerontological Society of America Annual Meeting. November 9, 2023. Tampa, FL.
  19. Healthy Brain Aging. Duke Continuing Studies Osher Lifelong Learning Institute. October 31, 2023.
  20. Alzheimer's Disease: Advances in Prevention, Diagnosis, and Treatment. Alzheimer's Foundation of America Educating America Tour. October 18, 2023. Raleigh, NC.
  21. The Genetics of Dementia and Genetic Testing. Duke Dementia Family Support Program. September 19, 2023. Virtual.
  22. Anti-Amyloid Therapy for Alzheimer's Disease. Department of Neurology Grand Rounds, Duke University School of Medicine. July 19, 2023.
  23. Promoting Healthy Brain Aging. Jewish for Good: Aging and Thriving Conference. April 19, 2023. Virtual.
  24. Does APOE genotype moderate the impact of CR on lipid-related cardiometabolic measures? 2023 CALERIE Summit. April 17, 2023. Phoenix, AZ.
  25. Treatment of Alzheimer's Disease. Duke Dementia Family Support Program. February 16, 2023. Virtual.
  26. Impact of Caloric Restriction on Biomarkers of ADRD Risk and the Role of Tryptophan Metabolism in ADRD. Wake Forest Sticht Center Conference on Aging. December 7, 2022. Winston-Salem, NC.
  27. Impact of Calorie Restriction on Plasma Aβ in CALERIE. Gerontological Society of America Annual Meeting. November 3, 2022. Indianapolis, IN.
  28. Dementia 101. Duke Caregiver Community Event. October 28, 2022.
  29. Advances in Alzheimer's Disease: Prevention, Diagnosis, and Treatment. VA COACH Program Retreat. September 15, 2022. Virtual.
  30. Dementia 101. Duke Caregiver Virtual Community Event. June 15, 2022.
  31. Advances in Alzheimer's Disease: Prevention, Diagnosis, and Treatment. Duke Department of Medicine LEADS Series. May 24, 2022.
  32. Pre-operative Biological Age Advancement is Associated with Longer Post-operative Length of Stay. American Geriatrics Society Annual Scientific Meeting. May 13, 2022. Orlando, FL.
  33. Associations of Plasma ADRD Biomarkers with Physical Performance in the Duke PALS Study. American Geriatrics Society Annual Scientific Meeting. May 13, 2022. Orlando, FL.
  34. Healthy Skeletal Muscle, Healthy Brain: Are Kynurenine Pathway Metabolites the Link? Johns Hopkins Biology of Healthy Aging Seminar Series. April 12, 2022. Virtual.
  35. Aducanumab: Anti-amyloid Therapy for Alzheimer's Disease. Division of Geriatrics Grand Rounds, Duke University School of Medicine. July 19, 2021.
  36. Emerging Blood Biomarkers of Alzheimer's Disease. Neuropsychology Grand Rounds, Duke University School of Medicine. May 20, 2021.
  37. Emerging Blood Biomarkers of Alzheimer's Disease. Department of Neurology Grand Rounds, Duke University School of Medicine. December 23, 2020.
  38. Emerging Blood Biomarkers of Alzheimer's Disease. Division of Geriatrics Grand Rounds, Duke University School of Medicine. December 7, 2020.
  39. Diagnosis and Management of Mild Cognitive Impairment and Dementia. Advanced Topics in Neurology CME Series, Duke University School of Medicine. August 8, 2020.
  40. Emerging Blood Biomarkers of Alzheimer's Disease. Advanced Topics in Neurology CME Series, Duke University School of Medicine. January 27, 2020.
  41. Are Biomarkers of Biological Age and Physical Resilience Associated with Surgical Outcomes? Department of Surgery Grand Rounds, Duke University School of Medicine. October 9, 2019.
  42. Biomarker Signatures of Cognitive Impairment in the Performance Across the Lifespan Study (PALS). American Geriatrics Society Annual Scientific Meeting. May 3, 2019. Portland, OR.
  43. Biomarker Signatures of Morbidity and Physical and Cognitive Impairment in PALS. Claude D. Pepper OAIC Annual Meeting. April 26, 2019. Arlington, VA.
  44. Biomarker Signatures of Morbidity and Physical and Cognitive Impairment in PALS. North Carolina Research Campus Spring 2019 Catalyst Symposium. April 1, 2019. Kannapolis, NC.
  45. (Social) Entrepreneurship in Aging. Duke Aging Center Post-Doctoral Research Seminar. January 9, 2019.
  46. Improving Health for Older Adults in Durham with Community Referrals: Technology Meets Reality (with G. Upchurch). Duke CTSI Synergy Population Health Improvement Seminar Series. April 11, 2018.
  47. Visual vs. Volumetric Assessment of Hippocampal Atrophy. EVMS Department of Medicine 35th Annual Research Day. 2016.
  48. HIV RNA in GALT Does Not Correlate with Plasma RNA Levels in Acute HIV Infection. Center for HIV/AIDS Vaccine Immunology Conference. September 10, 2008.

Research Support

Active

  • NIH/NIA 1R61-AG080615-01 — Impact of Time Restricted Feeding on Metabolic Flexibility in older adults with MCI. PI: Smith PJ. Role: Co-Investigator. February 2023 – January 2025. ~$527,985.
  • Eisai Inc. (AHEAD 3-45) — BAN2401 in preclinical Alzheimer's disease. PI: Johnson KJ. Role: Co-Investigator.
  • Annovis Bio (ANVS-22002) — Buntanetap in mild to moderate Alzheimer's disease. PI: Johnson KJ. Role: Co-Investigator.
  • Athira Pharmaceuticals (ATH-1017-AD-0201) — ATH-1017 in mild to moderate Alzheimer's disease. PI: Johnson KJ. Role: Co-Investigator.
  • Biogen Inc. (CELIA) — BIIB080 in MCI due to AD or mild AD dementia. PI: Liu A. Role: Co-Investigator.

Completed

  • Duke Department of Medicine Chair's Research Award — Calories on the Brain: Leveraging Insights from Calorie Restriction to Promote Healthy Brain Aging. PI: Parker DC. July 2022 – June 2023. ~$90,000.
  • NIH 1R01-HL153497-01A1 — Skeletal Muscle Molecular Drug Targets for Exercise-induced Cardiometabolic Health. PI: Kraus WE. Role: Co-Investigator. April 2021 – March 2026.
  • NIH/NIA 1R01-AG070146-01 — Extracellular Vesicle Analyses to Develop Aging and Resilience Biomarkers. PI: Kraus VB. Role: Co-Investigator. January 2021 – December 2025.
  • NIH/NIA GEMSSTAR 1R03AG067987-01 — Healthy Skeletal Muscle, Healthy Brain: Are Kynurenine Metabolites the Link? PI: Parker DC. July 2020 – June 2022. ~$200,000.
  • Duke Department of Surgery Gardner Award — Biological Age, Physical Resilience, and Surgical Outcomes in the 1KP. PI: Parker DC. June 2020 – June 2022. ~$50,000.
  • Duke Pepper Center Career Development Award — Biomarkers of Cognitive Resilience in the Duke PALS Study. PI: Parker DC. July 2020 – June 2022. ~$60,000.
  • Duke Center for Geriatric Surgery Scholars Award — Biological Age and Outcomes after CABG. PI: Parker DC. October 2019 – March 2022. ~$20,000.
  • NIH/NIA 5R01AG054840-02 — Epigenetic Mechanisms Promoting Longevity. PI: Kraus VB. Role: Co-Investigator. July 2019 – May 2023.
  • NIH/NIA 4UH3-AG056925-03 — Physical Resiliencies: Indicators and Mechanisms in the Elderly Collaborative. PI: Colón-Emeric CS. Role: Co-Investigator. September 2019 – August 2022.
  • CALERIE Biorepository Pilot Award (NIH/NIA 1U24AG047121) — Effect of Caloric Restriction on Plasma Markers of Brain Aging. PI: Parker DC. July 2019 – June 2020. ~$25,000.
  • Dementia Alliance of North Carolina — Lina Mae Edwards Young Investigator Research Award — Impact of Exercise Training on ADRD-related Biomarkers. PI: Parker DC. July 2019 – June 2021. ~$100,000.
  • NIH/NHLBI R01HL135009-02 — A Longitudinal Epigenetic Study of Atherosclerosis. PI: Liu Y. Role: Co-Investigator. March 2020 – November 2020.
  • NIH/NIA T32 AG000029 — Geriatric Medicine Research Training Grant. PI: Cohen HJ. Role: Post-doctoral Research Fellow. July 2017 – June 2019.
  • Duke CTSI Population Health Improvement Award — CAPSTONe: an online community resource referral platform. PI: Heflin MT. Role: Co-Investigator. July 2017 – June 2018.

Clinical Activities

Duke Memory Disorders Clinic — Duke Neurological Disorders Clinic at Morreene Road — January 2020 – Current (7 sessions/week since January 2024). Subspecialty geriatric medicine focused on memory disorders and dementia care, integrated with research in biomarkers of brain aging, cognitive resilience, and ADRD. Active anti-amyloid therapy program for early Alzheimer's disease.

Geriatrics Inpatient Consult Service — Duke University Hospital and Duke Regional Hospital — July 2019 – July 2022

Geriatrics Evaluation and Treatment Clinic — Duke South — July 2019 – December 2019

Professional Societies

  • American Geriatrics Society — Member, 2016 – Current
  • Gerontological Society of America — Member, 2019 – Current

Leadership and Volunteer Activities

  • President — Resident and Fellows Association, Eastern Virginia Medical School — 2014 – 2015
  • Co-Founder — HOPES Free Clinic, Eastern Virginia Medical School — 2010 – 2015 — Virginia's only student-run free clinic, now serving over 500 uninsured residents of Norfolk, VA.
  • Member — Student Honor Council, Eastern Virginia Medical School — 2009 – 2013
  • Student Ambassador — Eastern Virginia Medical School — 2010 – 2013
  • Co-Founder — EVMS Beyond Clinic Walls, a student-run home visit program for vulnerable older adults — 2009 – 2011
  • President — Students for the Advancement of Geriatrics Education, Eastern Virginia Medical School — 2009 – 2011

Professional Training

  • Faculty Development Academy — Duke University School of Medicine — 2019 – 2022
  • Summer Training Course on the Biology of Aging — Buck Institute for Research on Aging — June 2018
  • Intervention Development for Elderly Adults Workshop — Duke Pepper OAIC — 2017

Prior Work and Research Experience

  • Founder — OurCareDirect.com — 2012 – 2018 — A web-based care coordination application for patients, caregivers, and healthcare providers.
  • Research Associate — Therapies to Disrupt HIV Latency, UNC School of Medicine (PI: David Margolis, MD) — 2006 – 2009
  • Research Assistant — Neurobiology of Depression, UNC School of Medicine (PI: Sela Mager, PhD) — 2000 – 2002
  • Staff Writer — EVMS Journal of Medicine and Health Sciences — 2009 – 2010